摘要：AbstractDynamic SPECT imaging captures the dynamic process of the radioisotope washed in and out, to and from tissues and exchanged between biological compartments. One of the most common application field for dynamic SPECT imaging is investigating renal functions. The main goal of this study was to create realistic simulations of the kidney in order to support the development of dynamic SPECT reconstruction algorithms. We created and parametrized a compartment model of the kidney for simulating the dynamic behavior of the MAG3 radiopharmacon. Solving the model with a parameter set corresponding to the normal and to the pathological cases the SPECT data acquisition was simulated using the GATE Monte Carlo simulation toolkit.
