摘要：Abstract Marked hyperalphalipoproteinemia (HAL) is a heterogeneous syndrome. To clarify the pathophysiological significance of HAL, we compared clinical profiles between marked {HAL} subjects with and without cholesteryl ester transfer protein (CETP) deficiency. {CETP} deficiency was associated with cardiovascular diseases and strokes in the {HAL} population, particularly in female. {HAL} women without {CETP} deficiency tended to have higher prevalence with cancer history. {HAL} may not always be a longevity marker, but be sometimes accompanied with pathological conditions.
关键词：Atherosclerosis; Cardiovascular disease; Cholesteryl ester transfer protein deficiency; High density lipoprotein; Hyperalphalipoproteinemia; Stroke
Loading...
