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  • 标题:Visible-light driven regioselective synthesis, characterization and binding studies of 2-aroyl-3-methyl-6,7-dihydro-5 H-thiazolo[3,2- a]pyrimidines with DNA and BSA using biophysical and computational techniques
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  • 作者:Ranjana Aggarwal ; Naman Jain ; Shilpa Sharma
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2021
  • 卷号:11
  • DOI:10.1038/s41598-021-01037-4
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:In recent times, fused azaheterocycles emerged as impressive therapeutic agents. Binding studies of such azaheterocycles with biomolecules is an important subject for pharmaceutical and biochemical studies aiming at the design and development of new drugs. Fused heterocyclic scaffolds, such as thiazolopyrmidines have long been used in the pharmaceutical industry for the treatment of various diseases. In this study, we have accomplished a regioselective synthesis of 2-aroyl-3-methyl-6,7-dihydro-5 H-thiazolo[3,2- a
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