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  • 标题:Therapeutic effects of acylated ghrelin-specific receptor GHS-R1a antagonist in islet transplantation
  • 本地全文:下载
  • 作者:Kiyoshi Chinen ; Naoaki Sakata ; Gumpei Yoshimatsu
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2021
  • 卷号:11
  • DOI:10.1038/s41598-021-00740-6
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:Islet transplantation is a type of cellular replacement therapy for severe diabetes that is limited by compromising effect on engrafted islets. Trials aiming to improve the function of transplanted islets have also been challenging. This study attempted to elucidate whether regulation of growth hormone secretagogue receptor-1a (GHS-R1a), one of the ghrelin receptors, improve the therapeutic effects of islet transplantation using [D-Lys3
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