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  • 标题:An open-label, randomized, single intravenous dosing study to investigate the effect of fixed-dose combinations of tenofovir/lamivudine or atazanavir/ritonavir on the pharmacokinetics of remdesivir in Ugandan healthy volunteers (RemTLAR)
  • 本地全文:下载
  • 作者:Stephen I. Walimbwa ; Julian P. Kaboggoza ; Catriona Waitt
  • 期刊名称:Trials
  • 印刷版ISSN:1745-6215
  • 电子版ISSN:1745-6215
  • 出版年度:2021
  • 卷号:22
  • DOI:10.1186/s13063-021-05752-1
  • 语种:English
  • 出版社:BioMed Central
  • 摘要:Background Remdesivir is a novel broad-spectrum antiviral therapeutic with activity against several viruses that cause emerging infectious diseases. The purpose of this study is to explore how commonly utilized antiretroviral therapy (tenofovir disoproxil fumarate/lamivudine [TDF/3TC
  • 关键词:Remdesivir; COVID-19; Ebola; HIV; Atazanavir; Ritonavir; Tenofovir; Lamivudine; Drug-drug interactions
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