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  • 标题:Association between prehospital arterial hypercapnia and mortality in acute heart failure: a retrospective cohort study
  • 本地全文:下载
  • 作者:Mathias Fabre ; Christophe A. Fehlmann ; Kevin E. Boczar
  • 期刊名称:BMC Emergency Medicine
  • 印刷版ISSN:1471-227X
  • 电子版ISSN:1471-227X
  • 出版年度:2021
  • 卷号:21
  • DOI:10.1186/s12873-021-00527-y
  • 语种:English
  • 出版社:BioMed Central
  • 摘要:Background Acute Heart Failure (AHF) is a potentially lethal pathology and is often encountered in the prehospital setting. Although an association between prehospital arterial hypercapnia in AHF patients and admission in high-dependency and intensive care units has been previously described, there is little data to support an association between prehospital arterial hypercapnia and mortality in this population. Methods This was a retrospective study based on electronically recorded prehospital medical files. All adult patients with AHF were included. Records lacking arterial blood gas data were excluded. Other exclusion criteria included the presence of a potentially confounding diagnosis, prehospital cardiac arrest, and inter-hospital transfers. Hypercapnia was defined as a PaCO 2 higher than 6.0 kPa. The primary outcome was in-hospital mortality, and secondary outcomes were 7-day mortality and emergency room length of stay (ER LOS). Univariable and multivariable logistic regression models were used. Results We included 225 patients in the analysis. Prehospital hypercapnia was found in 132 (58.7%) patients. In-hospital mortality was higher in patients with hypercapnia (17.4% [23/132
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