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  • 标题:Maslinic Acid Promotes Hypertrophy Induced by Functional Overload in Mouse Skeletal Muscle.
  • 本地全文:下载
  • 作者:Takanaga Shirai ; Kazuki Uemichi ; Kakeru Kubota
  • 期刊名称:Journal of Nutritional Science and Vitaminology
  • 印刷版ISSN:0301-4800
  • 电子版ISSN:1881-7742
  • 出版年度:2021
  • 卷号:67
  • 期号:5
  • 页码:317-322
  • DOI:10.3177/jnsv.67.317
  • 语种:English
  • 出版社:Center for Academic Publications Japan
  • 摘要:Nutritional supplements are sometimes important for athletes to improve their sports performance and maintain their condition. Maslinic acid (MA) is a type of compound with a pentacyclic triterpene structure extracted from olives, and has a strong anti-inflammatory effect and improves metabolic function. This study aimed to investigate the effects of MA on muscle hypertrophy by functional overload using an animal model. Mice plantaris muscles were overloaded by synergist ablation surgery with/without MA and they were sampled at 4, 7, and 14 d after the operation. We demonstrated that MA significantly increased plantaris' cross-sectional area and activated the mechanistic target of rapamycin (mTOR) signaling compared with the non-supplemented group (main effect of MA, p
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