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  • 标题:Decoding gut microbiota by imaging analysis of fecal samples
  • 本地全文:下载
  • 作者:Chikara Furusawa ; Kumi Tanabe ; Chiharu Ishii
  • 期刊名称:iScience
  • 印刷版ISSN:2589-0042
  • 出版年度:2021
  • 卷号:24
  • 期号:12
  • 页码:1-14
  • DOI:10.1016/j.isci.2021.103481
  • 语种:English
  • 出版社:Elsevier
  • 摘要:SummaryThe gut microbiota plays a crucial role in maintaining health. Monitoring the complex dynamics of its microbial population is, therefore, important. Here, we present a deep convolution network that can characterize the dynamic changes in the gut microbiota using low-resolution images of fecal samples. Further, we demonstrate that the microbial relative abundances, quantified via 16S rRNA amplicon sequencing, can be quantitatively predicted by the neural network. Our approach provides a simple and inexpensive method of gut microbiota analysis.Graphical abstractDisplay OmittedHighlights•A deep convolution network classifies gut microbiota based on fecal sample images•Image-based quantitative prediction of gut microbiota composition is demonstrated•This result provides a simple and inexpensive method of gut microbiota analysisBiochemistry methods; Microbiome
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