摘要：ACUTE PANCREATITIS IS AN INFLAMMATORY CONDITION OF THE PANCREAS WITH MULTIPLE ETIOLOGIES. HYPERTRIGLYCERIDAEMIC PANCREATITIS (HTG-AP) IS NOT A COMMON CAUSE OF AP BUT IS ASOCIATED WITH A INCREASED RATE OF COMPLICATIONS. PATIENTS WITH DIABETES MELLITUS ARE AT INCREASED RISK OF AP. THE ASSOCIATIN BETWEEN HYPERTRIGLYCERIDAEMIA, KETOACIDOSIS AND AP IS RARE. THE TREATMENT OF THIS TYPE OF PANCREATITIS IS NOT WELL ESTABLISHED IN CURRENT GUIDELINES, SPECIFIC TERAPEUTIC MEASUREMENTS INCLUDE HEPARIN, INSULIN TREATMENT, PLASMAPHERESIS, COMBINED BLOOD PURIFICATION THERAPY, HIGH-VOLUME HEMOFILTRATION AND HEMOPERFUSION. WE REPORTED TWO CASES OF HYPERTRIGLYCERIDAEMIA (HTG) INDUCED AP, IN PACIENTS WITH UNCONTROLLED TYPE 2 DIABETES MELLITUS AND KETOACIDOSIS ONE TREATED WITH INSULIN INFUSION AND ANOTHER TREATED WITH INSULIN INFUSION AND PLASMAPHERESIS. BOTH CASES WERE SUCCESSFULLY MANAGED WITH SPECIFIC MEASURES AND SUPPORTIVE CARE.
