摘要:PITYRIASIS RUBRA PILARIS (PRP) IS AN INFLAMMATORY SKIN DISEASE WITH POLYMORPHIC CLINICAL FEATURES, CONSISTING OF KERATOSIC FOLLICULAR PAPULES, YELLOW-ORANGE PALMOPLANTAR KERATODERMA ASSOCIATED WITH ERYTHEMATOUS OR ERYTHEMATOUS SQUAMOUS PLAQUES, WHICH INTERSPERSED WITH AREAS OF HEALTHY SKIN. WE PRESENT THE CASE OF A 72-YEAR-OLD MAN IN WHICH THE DIAGNOSIS OF PRP REQUIRED ADDITIONAL EXPLORATIONS, FOR EXCLUDING NEOPLASIA OR OTHER INFLAMMATORY DISEASE. FINDING CONCOMITANT LIVER DISEASE REQUIRED A REASSESSMENT OF THERAPY.