摘要:Frimpong E, Ofori EK, Kaoje SY, Ababio E, Dzudzor B. Muscle Damage and Repeated Bout Effect from High Intensity NonEccentric Exercises. JEPonline 2019;22(5):126-140. The purpose of this study was to estimate the extent of muscle damage and the Repeated Bout effect from high intensity non-eccentric aerobic exercises compared to an eccentric exercise. Thirty healthy subjects were randomized into either the downhill, uphill, or level treadmill group. The groups performed treadmill running at 70% of heart rate reserve (HRR) for 30 min in Bout 1. Two weeks later, the subjects performed a Repeated Bout of downhill treadmill running at 80% of HRR for 35 min. Creatine kinase (CK), total white blood cells (TWBC), muscle soreness (SOR) and mid-thigh circumference (MC) were assessed as markers of muscle damage before and at 1, 24, and 48 hrs after each exercise bout. Muscle damage was significantly higher in the downhill group than the uphill or level treadmill group after the Bout 1 exercises (P<0.05). However, muscle damage was significantly higher in the uphill and level treadmill groups than the downhill group following the Repeated Bout. Novel high intensity non-eccentric exercises do not adequately protect muscles against damaging exercises.