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  • 标题:Influence of Ethnicity and Gene Polymorphism T-786C eNOS on Post-Exercise Hypotension in Hypertensive Adults
  • 本地全文:下载
  • 作者:Sena KF ; Sena KF ; Pursunh DC
  • 期刊名称:Journal of exercise physiology online
  • 印刷版ISSN:1097-9751
  • 出版年度:2020
  • 卷号:23
  • 期号:2
  • 页码:61-70
  • 语种:English
  • 出版社:American Society of Exercise Physiologists
  • 摘要:Sena KF, Pursunh DC, Zanesco A, Rodrigues TR, Martins CCL,Cavalcanti-Dantas VM, Cardoso GA, Nascimento EDS, RibeiroMD, Silva AS. Influence of Ethnicity and Gene Polymorphism T786C eNOS on Post-Exercise Hypotension in Hypertensive Adults.JEPonline 2020; 23(2):61-70. The purpose of this study was to verifythe influence of ethnicity and polymorphism on the eNOS T-786Cgene (rs2070744) in the response of blood pressure to an exercisesession. Eighty-nine hypertensive subjects (age, 57.6 ± 8.7 yrs; 26with white skin and 63 with dark skin) were initially genotyped andsubmitted to a 60-min running/walking session of moderate intensity.Their blood pressure was measured before exercise, immediatelyafter exercise, and every 10 min of a 60-min recovery period afterexercise. There was a decrease in post-exercise systolic bloodpressure of 6.9 ± 11.0 mmHg at 10 min, which increased to 10.9 ±12.0 mmHg at 20 min. Then, it remained stable for the rest of therecovery period. Ethnicity and genotype did not modify theseresponses. The results indicate that hypertensive subjects with darkskin also benefit by the phenomenon of post-exercise hypotension.
  • 关键词:Aerobic Exercise;Ethnic Groups;Genetic Polymorphism;Post-Exercise Hypotension
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