In this study we determined the correlation of axial length to lamina cribrosa thickness (LCT), prelaminar tissue thickness (PT), and anterior laminar displacement (ALD) in young healthy eyes.

The optic discs of 60 eyes from 30 young healthy subjects with myopia were scanned using enhanced-depth imaging spectral-domain optical coherence tomography (Spectralis OCT, Heidelberg Engineering, Heidelberg, Germany). The LCT, PT, and ALD were measured at the superior midperipheral, middle, and inferior midperipheral of the optic nerve head, respectively. A linear mixed-effects model was used to determine the relationship between the axial length and the LCT, axial length and PT as well as axial length and ALD.

The mean, superior midperipheral, and middle LCT were not significantly correlated with axial length. Conversely, the inferior midperipheral LCT was negatively correlated with axial length ( p = 0.019, β = -7.34). There was no significant association between axial length and PT. Mean ALD was negatively correlated with axial length ( p = 0.022, β = -17.17).

In the present study, the inferior midperipheral LCT and mean ALD were negatively correlated with axial length, but PT showed no significant association with axial length.