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  • 标题:Resistant Starch Consumption Effects on Glycemic Control and Glycemic Variability in Patients with Type 2 Diabetes: A Randomized Crossover Study
  • 本地全文:下载
  • 作者:Yolanda Arias-Córdova ; Jorge Luis Ble-Castillo ; Carlos García-Vázquez
  • 期刊名称:Nutrients
  • 电子版ISSN:2072-6643
  • 出版年度:2021
  • 卷号:13
  • 期号:11
  • DOI:10.3390/nu13114052
  • 语种:English
  • 出版社:MDPI Publishing
  • 摘要:We previously observed beneficial effects of native banana starch (NBS) with a high resistant starch (RS) content on glycemic response in lean and obese participants. Here, we aimed to determine the effects of NBS and high-amylose maize starch (HMS) on glycemic control (GC) and glycemic variability (GV) in patients with type 2 diabetes (T2D) when treatments were matched for digestible starch content. In a randomized, crossover study, continuous glucose monitoring (CGM) was performed in 17 participants (aged 28–65 years, BMI ≥ 25 kg/m 2, both genders) consuming HMS, NBS, or digestible maize starch (DMS) for 4 days. HMS and NBS induced an increase in 24 h mean blood glucose during days 2 to 4 ( p < 0.05). CONGA, GRADE, and J-index values were higher in HMS compared with DMS only at day 4 ( p < 0.05). Yet, NBS intake provoked a reduction in fasting glycemia changes from baseline compared with DMS ( p = 0.0074). In conclusion, under the experimental conditions, RS from two sources did not improve GC or GV. Future longer studies are needed to determine whether these findings were affected by a different baseline microbiota or other environmental factors.
  • 关键词:resistant starch; banana; glycemic variability; glycemic control; type 2 diabetes; continuous glucose monitoring
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