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  • 标题:AMPK Activity: A Primary Target for Diabetes Prevention with Therapeutic Phytochemicals
  • 本地全文:下载
  • 作者:Min-Yu Chung ; Hyo-Kyoung Choi ; Jin-Taek Hwang
  • 期刊名称:Nutrients
  • 电子版ISSN:2072-6643
  • 出版年度:2021
  • 卷号:13
  • 期号:11
  • DOI:10.3390/nu13114050
  • 语种:English
  • 出版社:MDPI Publishing
  • 摘要:Diabetes is a metabolic syndrome characterized by inadequate blood glucose control and is associated with reduced quality of life and various complications, significantly shortening life expectancy. Natural phytochemicals found in plants have been traditionally used as medicines for the prevention of chronic diseases including diabetes in East Asia since ancient times. Many of these phytochemicals have been characterized as having few side effects, and scientific research into the mechanisms of action responsible has accumulated mounting evidence for their efficacy. These compounds, which may help to prevent metabolic syndrome disorders including diabetes, act through relevant intracellular signaling pathways. In this review, we examine the anti-diabetic efficacy of several compounds and extracts derived from medicinal plants, with a focus on AMP-activated protein kinase (AMPK) activity.
  • 关键词:diabetes; AMP-activated protein kinase; medicinal plants; ingredient
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