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  • 标题:The present and future of veterinary vaccines for Japanese encephalitis in Korea
  • 本地全文:下载
  • 作者:Nah, Jin-Ju ; Yang, Dong-Kun ; Kim, Ha-Hyun
  • 期刊名称:Clinical and Experimental Vaccine Research
  • 印刷版ISSN:2287-3651
  • 出版年度:2015
  • 卷号:4
  • 期号:2
  • 页码:130-136
  • DOI:10.7774/cevr.2015.4.2.130
  • 语种:English
  • 出版社:KoreaMed Synapse
  • 摘要:

    Japanese encephalitis (JE) is a mosquito-borne zoonotic disease that affects approximately 50,000 people annually in Asia, causing 10,000 deaths. Considering the role of pigs as the virus-amplifying host and the economic loss in the swine industry, JE is an important disease for both public and animal health. A nationwide JE virus (JEV) vaccination program has been conducted annually for more than 30 years to prevent severe reproductive disorders in the Korean sow population. Remarkable progress in molecular biology has made it possible to analyze the genome of the vaccine strain at the nucleotide and amino acid levels. However, the scientific record of the current JEV veterinary vaccine has not been reported. Therefore, this article outlines the current JEV vaccine strain used in animals and discusses future directions for developing new veterinary JEV vaccines.

  • 关键词:Japanese Encephalitis; Japanese encephalitis viruses; Vaccines; Attenuated; Animals
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