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  • 标题:Step-by-step assembly and testing of a low-cost bioprinting solution for research and educational purposes
  • 本地全文:下载
  • 作者:John Robert Honiball ; Michael Sean Pepper ; Earl Prinsloo
  • 期刊名称:MethodsX
  • 印刷版ISSN:2215-0161
  • 电子版ISSN:2215-0161
  • 出版年度:2021
  • 卷号:8
  • 页码:1-9
  • DOI:10.1016/j.mex.2020.101186
  • 语种:English
  • 出版社:Elsevier
  • 摘要:AbstractBioprinting is a rapidly expanding technology with the ability to fabricate in vitro three-dimensional (3D) tissues in a layer-by-layer manner to ultimately produce a living tissue which physiologically resembles native in vivo tissue functionality. Unfortunately, large costs associated with commercially available bioprinters severely limit access to the technology. We investigated the potential for modifying a low-cost commercially available RepRap Prusa iteration 3 (i3) 3D printer with an open-source syringe-housed microextrusion print-head unit (universal paste extruder by Richard Horne, RichRap), that allowed for controlled deposition of cell-laden bioinks and Freeform Reversible Embedding of Suspended Hydrogels (FRESH) method-based printing.Graphical abstractDisplay Omitted
  • 关键词:Bioprinting;Sodium alginate;Freeform reversible embedding of suspended hydrogels (FRESH);Additive manufacturing
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