摘要：The aim of this study was to investigate deter- mination of antioxidant capacity and changes of bi- ochemical parameters [ Albumin. ALP (Alkaline phosphatase), ALT (Alanin transaminase), AST (As- partate aminotransferase). cholesterol, CK-MB (Creatine kinase), GGT (Gama-glutamil transferase),T-Protein, Triglycerine, BUN (Blood Urea Nitrogen)] on calves persistently infected (PI) with Bovine viral diarrhea virus (BVDV) in Konya. Blood samples (both sera and leukocyte) will be taken from the PI calves. Obtained samples will be screened for BVDV antigen and antibodies, antioxidant capacity and changes of biochemical parameters with the use of a commercially available Enzyme Linked Im- munosorbent Assay (ELISA) kits. Independent T testwill be performed for comparing results between PI calves and a control group. P<0.05 value will be con- sidered significance level. A statistically significant difference was found between ALB, ALP, Choles- terol, CK-MB. TP values (P <0.05) while there was no statistically significant difference MDA and TAC values between control and study group (p>0.05). It can be communicable that persistently BVDV infection has been damage the heart, duodenum and liver, although affecting lipid metabolism and lipid peroxidation. In conclusion the fact that the PI animals to be detected are to be re- moved from farms is of economic importance both our province and others. In addition, changes in bio- chemical parameters and antioxidant capacities inpersistent infected animals will give some infor- mation about the pathogenesis of the infection.
