摘要：Graphical Display OmittedBoswellia sp. is a species of Boswellia.Burseraceaeis an essential conventional natural product that has received a lot of attention in the pharmaceutical industry in recent years. The aim of this study was to role ofBoswelliasp.Burseraceaeon kidney and liver of Balb/c mice. Different concentrationsof Boswelliasp. Burseraceae solution was given to 5–7 weeks old wild-type Balb/c mice of both sexes (n = 24) for 21 days, with a control group given normal water to determine the physiological, biochemical, haematological, (0.5%, 1%), and histopathological effect of (0.5%, 1% and 5%)Boswelliasp..The results of this study showed that physiological parameters were changed with the increasing concentration ofBoswelliasp.Burseraceaesolution; like daily food consumption was reduced and fluid intake was more, decrease in body weight, urine output was low with less Na+& K+resulting into hypernatremia, hyperkalemia and hyperuricemia. Also elevated creatinine level in blood increase levels of bilirubin, Aspartate Aminotransferase (AST), Alanine Aminotransferase (ALT), Alkaline Phosphatase (ALP) and degeneration of cells, glomerular atrophy of kidney cells and degeneration of hepatocytes. In conclusion, all of the results support to dosage toxicity. Biochemical indicators such as white blood cells, glucose, and haemoglobin did not alter significantly. Based on the findings, it is concluded that the extract exhibits dosage toxicity, which is corroborated by histopathological indicators.
