摘要：SummaryCommunication is a keystone of animal behavior. However, the physiological states underlying natural vocal signaling are still largely unknown. In this study, we investigated the correlation of affective vocal utterances with concomitant cardiorespiratory mechanisms. We telemetrically recorded electrocardiography, blood pressure, and physical activity in six freely moving and interacting cynomolgus monkeys (Macaca fascicularis). Our results demonstrate that vocal onsets are strengthened during states of sympathetic activation, and are phase locked to a slower Mayer wave and a faster heart rate signal at ∼2.5 Hz. Vocalizations are coupled with a distinct peri-vocal physiological signature based on which we were able to predict the onset of vocal output using three machine learning classification models. These findings emphasize the role of cardiorespiratory mechanisms correlated with vocal onsets to optimize arousal levels and minimize energy expenditure during natural vocal production.Graphical abstractDisplay OmittedHighlights•Cardiovascular signals are measured telemetrically in freely moving macaques•A distinct cardiovascular physiological signature is present before vocal onset•Vocal onsets are phase locked to the Mayer wave and heart rate signals•Vocal onsets prediction is performed using machine learning classification modelsCardiovascular medicine; Biological sciences; Ethology; Behavioral neuroscience
