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  • 标题:Multimodal neural probes for combined optogenetics and electrophysiology
  • 本地全文:下载
  • 作者:Huihui Tian ; Ke Xu ; Liang Zou
  • 期刊名称:iScience
  • 印刷版ISSN:2589-0042
  • 出版年度:2022
  • 卷号:25
  • 期号:1
  • 页码:1-15
  • DOI:10.1016/j.isci.2021.103612
  • 语种:English
  • 出版社:Elsevier
  • 摘要:SummaryTo understand how brain functions arise from interconnected neural networks, it is necessary to develop tools that can allow simultaneous manipulation and recording of neural activities. Multimodal neural probes, especially those that combine optogenetics with electrophysiology, provide a powerful tool for the dissection of neural circuit functions and understanding of brain diseases. In this review, we provide an overview of recent developments in multimodal neural probes. We will focus on materials and integration strategies of multimodal neural probes to achieve combined optogenetic stimulation and electrical recordings with high spatiotemporal precision and low invasiveness. In addition, we will also discuss future opportunities of multimodal neural interfaces in basic and translational neuroscience.Graphical abstractDisplay OmittedNeuroscience; Biotechnology; Materials science
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