标题：Estimates of voluntary activation in individuals with anterior cruciate ligament reconstruction: Effects of type of stimulator, number of stimuli, and quantification technique
摘要：Highlights
•
Voluntary activation was consistently overestimated when using the central activation ratio compared with the percent activation derived from the interpolated twitch technique.
•
Constant current and constant voltage electrical stimulators yield similar estimates of voluntary activation in those with anterior cruciate ligament reconstruction.
•
Activation estimates derived using the central activation ratio are affected by the number of electrical pulses used during testing.
•
The interpolated twitch technique yields better estimates of voluntary activation and is less affected by pulse train conditions or stimulators used during the testing.
Background
Accurate quantification of voluntary activation is important for understanding the extent of quadriceps dysfunction in individuals with anterior cruciate ligament reconstruction (ACLR). Voluntary activation has been quantified using both percent activation derived from the interpolated twitch technique and central activation ratio (CAR) derived from the burst superimposition technique, as well as by using different types of electrical stimulators and pulse train conditions. However, it is unclear how these parameters affect voluntary activation estimates in individuals with ACLR. This study was performed to fill this important knowledge gap in the anterior cruciate ligament literature.
Methods
Quadriceps strength and voluntary activation were examined in 18 ACLR participants (12 quadriceps/patellar tendon graft, 6 hamstring tendon graft; time since ACLR: 1.06 ± 0.82 years, mean ± SD) at 90° of knee flexion using 2 stimulators (Digitimer and Grass) and pulse train conditions (3-pulse and 10-pulse). Voluntary activation was quantified by calculating both CAR and percent activation.
Results
Results indicated that voluntary activation was significantly overestimated by CAR when compared with percent activation (
p < 0.001). Voluntary activation estimates were not affected by pulse train conditions when using percent activation; however, 3-pulse stimuli resulted in greater overestimation than 10-pulse stimuli when using CAR (
p = 0.003). Voluntary activation did not differ between stimulators (
p > 0.05); however, the Digitimer evoked greater torque at rest than the Grass (
p < 0.001).
Conclusion
These results indicate that percent activation derived from the interpolated twitch technique provides superior estimates of voluntary activation than CAR derived from burst superimposition and is less affected by pulse train conditions or stimulators in individuals with ACLR.
Graphical abstract
Image, graphical abstract
