摘要：SummaryMany experimental studies have examined behavioral and electrophysiological responses of mosquitoes to odors. However, the differences across studies in data collection, processing, and reporting make it difficult to perform large-scale analyses combining data from multiple studies. Here we extract and standardize data for 12 mosquito species, along withDrosophila melanogasterfor comparison, from over 170 studies and curate the Mosquito Olfactory Response Ensemble (MORE), publicly available athttps://neuralsystems.github.io/MORE. We demonstrate the ability of MORE in generating biological insights by finding patterns across studies. Our analyses reveal that ORs are tuned to specific ranges of several physicochemical properties of odorants; the empty-neuron recording technique for measuring OR responses is more sensitive than theXenopusoocyte technique; there are systematic differences in the behavioral preferences reported by different types of assays; and odorants tend to become less attractive or more aversive at higher concentrations.Graphical abstractDisplay OmittedHighlights•MORE is a database of behavioral and electrophysiological responses to odors•MORE includes data from 170 studies covering 12 species of mosquitoes along with flies•MORE shows differences in odor preferences measured with different assays•Empty-neuron technique measures responses more sensitively than the oocyte techniqueBiological sciences; Computer science applications; Entomology; Neuroscience
