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  • 标题:An Additive Sparse Logistic Regularization Method for Cancer Classification in Microarray Data
  • 本地全文:下载
  • 作者:Vijay Suresh Gollamandala ; Lavanya Kampa
  • 期刊名称:The International Arab Journal of Information Technology
  • 印刷版ISSN:1683-3198
  • 出版年度:2021
  • 卷号:18
  • 期号:2
  • DOI:10.34028/iajit/18/2/10
  • 语种:English
  • 出版社:Zarqa Private University
  • 摘要:Now a day’s cancer has become a deathly disease due to the abnormal growth of the cell. Many researchers are working in this area for the early prediction of cancer. For the proper classification of cancer data, demands for the identification of proper set of genes by analyzing the genomic data. Most of the researchers used microarrays to identify the cancerous genomes. However, such kind of data is high dimensional where number of genes are more compared to samples. Also the data consists of many irrelevant features and noisy data. The classification technique deal with such kind of data influences the performance of algorithm. A popular classification algorithm (i.e., Logistic Regression) is considered in this work for gene classification. Regularization techniques like Lasso with L1 penalty, Ridge with L2 penalty, and hybrid Lasso with L1/2+2 penalty used to minimize irrelevant features and avoid overfitting. However, these methods are of sparse parametric and limits to linear data. Also methods have not produced promising performance when applied to high dimensional genome data. For solving these problems, this paper presents an Additive Sparse Logistic Regression with Additive Regularization (ASLR) method to discriminate linear and non-linear variables in gene classification. The results depicted that the proposed method proved to be the best-regularized method for classifying microarray data compared to standard methods.
  • 关键词:Microarray data;sparse regularization;feature selection;logistic regression;and lasso
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