摘要:Objective of the study: the objective of this research is to analyze how entrepreneurial universities in the Boston region, USA, contribute to the local innovation ecosystem. Methodology / approach: used was the qualitative paradigm, classified as a multiple case study and with data collection through semi-structured interviews, document analysis and observation. For analysis used for strategic content analysis. Originality / relevance: this research aims to contribute to society and dedicate itself to reflecting on the role of the university in modern society. The entrepreneurial universities provided a relevant research field, since this model of academic institution presented economic and social potential for regions where it is located. Main results: as contributions by universities to the ecosystem: training of technologically selected students; building an entrepreneurial mindset in students; research groups with a multidisciplinary character; collaborative research groups with industries and companies; research groups for requested demands; competitions that include extra-university students; formation of start-ups with business model validation; contribution to economic development through the application of financial resources received and contribution to social development by fostering the development of the region. Theoretical / methodological contributions: this study helps to identify the elements that make up an entrepreneurial university in a joint analysis of six universities in the Boston region; to characterize Boston's innovation ecosystem, which deals with branding an item for the university segment and to identify the set of actions and infrastructures connected as entrepreneurial universities to the ecosystem.