摘要:The Cooperative is a "pillar of the Indonesian economy" which needs to be managed professionally, as stipulated in article 33 of the 1945 Constitution of the Republic of Indonesia. Articles of this research explain determinant factors for the performance of cooperative managers in Ambon City. The population studied included administrators, supervisors and managers of 200 active cooperatives or from 176 cooperatives with managers. Determination of the sample was carried out through a simple random technique, so that the number of respondents representing each population group (managers, administrators, and supervisors of cooperatives) was 64 people each. The analysis technique used is multiple regression. The results of the study found that there are two determinant factors namely intellectual capital and entrepreneurship significantly influence cooperative business performance, while the business strategy has no significant effect on cooperative business performance in Ambon City. It is recommended that regional government officials and stakeholder cooperatives in Ambon City pay attention to the availability and empowerment of management intellectual capital with members of cooperatives, provide financial support for cooperative managers to benchmarking entrepreneurial insights, and design cooperative business strategies that are profitable and relevant to regional potential and competitive conditions the business faced, both with fellow cooperatives and with other economic actors so that cooperatives continue to exist, survive, and develop as pillars of the local and national economy.