标题：Comparison of the anxiolytic effects of bitter orange (Citrus Aurantium. L) and Diazepam before ophthalmic surgery: a single-blind randomized clinical trial
摘要：Anxiety is an unpleasant feeling that affects the comfort and health of the patient. Surgery-related anxiety is defined as the specific stress, the patient experience when exposed to surgery. The aim of this study is to compare the effects of citrus Aurantium and diazepam on the preoperative anxiety of patients who were candidates for ophthalmic surgery. In this single blind clinical trial study, a total of 67 patients who referred to Bou Ali Sina hospital (Sari, Iran) for ophthalmic surgery were selected and randomly divided into 2 groups. The night before surgery, the patients of group 1 (33 cases) received 100 cc of citrus Aurantium blossom distillate while the patients in group 2 (34 cases) received 1 diazepam pill (5 mg) dissolved in 100cc water. The level of patients’ anxiety was measured by using Spielberger Stait-Trait Anxiety Inventory (STAI) before intervention, and the next morning (immediately after entering the operating room). Regarding the demographic data, the study population was homogenous. In both of citrus Aurantium and diazepam groups, the mean of trait anxiety was reduced from 49.12±3.67 to 46.87±3.87 and 49.26±3.68 to 46.91±3.26 respectively. Considering the finding, both citrus Aurantium and diazepam have the same effect on anxiety; and can serve them as a premedication for soothing preoperative anxiety.
