摘要：AbstractObjectivesBerberis lycium, Adhatoda vasica,andZizypus jujubaare common worldwide medicinal plants. These plants are used in different diseases by local people. However, the scientific rationale for the use of these plants is limited especially in diseases arising from oxidative stress. This study was therefore aimed to evaluate the antioxidant, antidiabetic, and anti-gout activity of these plants from Kashmir flora.MethodsThe antioxidant activities were studied by differentin vitro assayswhich include lipid peroxidation assay, DPPH assay, ABTS assay, iron chelation assay, total phenolic and flavonoid contents. The antidiabetic activity of plants extracts was analyzed by the inhibition of alpha glucosidase, while anti-gout activities were observed by the inhibition of xanthine oxidase enzyme.ResultsAll plants extract exhibited good antioxidant activities which are due to significant metal chelating ability and inhibition of lipid peroxidation. The maximum inhibitory effect against lipid peroxidation was observed in water extract ofBerberis lyciumroot extracts. The maximum antidiabetic activity was shown by acetone extract ofBerberis lyceumroots justifying its popular use in diabetes. Acetone extract ofZizypus jujubashowed excellent inhibition of xanthine oxidase justifying its popular use in gout. The high antioxidant and enzyme inhibitory activities of these plants might be due to high phenolic and flavonoid contents.ConclusionBased on these results, it is concluded thatZizpus jujuba,Adhatoda vasicaandBerberis lyciumare rich source of antioxidants and may be utilized as antidiabetic and antigout agents.
