摘要：AbstractThe present study estimates the antimicrobial potential of root extract ofAndrographis paniculatawhich are extensively used in traditional medicine against clinical pathogens. Thein vitroantibacterial activities were done with ten pathogen bacterial strains. Among the three extracts, the methanol extract exhibited the highest zone of inhibition againstSalmonella typhimurium(45 mm), while ethanol and ethyl acetate extract revealed strongin vitroantibacterial againstShigella flagella(42 mm) andE. faecalis(38 mm), respectively at 200 µg/ml concentration. Antifungal activities of ethanol and methanol extract were done against four reference fungal strains. The ethanol and methanol extract confirmed the highest antifungal activity againstTrichophyton mentagrophytes(38 mm) andCandida albicans(38 mm), respectively. The constituents of the fixed oil of petroleum ether root extract were evaluated by Gas Chromatography-Mass Spectrophotometer. Eleven composites have recognized, methyl palmitate (56.732%) was the major constituent. The investigation come to an end that the phytochemical constituents of methanol and ethanol root extract have capacity to kill both drug resistant bacteria and fungal.
