摘要：People with cystic fibrosis (pwCF) face great challenges during the ongoing COVID-19 pandemic. Recent research found equal levels of distress in pwCF and healthy controls (HC). The current study aimed to investigate the mental health burden and safety behavior in pwCF. Sixty-nine adult pwCF and sixty-nine propensity-score-matched HC participated in this study. Participants completed an anonymous online questionnaire assessing distress, generalized anxiety, depressive symptoms, COVID-19-related variables, self-reported adherent safety behavior (ASB), and dysfunctional safety behavior (DSB). PwCF showed equal amounts of distress (
W = 2481.0,
p = 0.669), depressive symptoms (
W = 2632.5,
p = 0.268), and generalized anxiety symptoms (
W = 2515.5,
p = 0.565) compared to the HC. COVID-19-related fear (
W = 1872.0,
p = 0.028), ASB (
W = 1630.0,
p = 0.001), and DSB (
W = 1498.5,
p < 0.001) were significantly elevated in pwCF. The pwCF estimated that the probability of suffering from symptoms (
W = 954.5,
p < 0.001), experiencing a severe course (
W = 806.5,
p < 0.001), or dying (
W = 1079.0,
p < 0.001) from COVID-19 is significantly higher than that of the HC. ASB was associated with a CF diagnosis, COVID-19-related fear, and a subjective level of information (
R
2
= 0.414,
F(13, 124) = 6.936,
p ≤ 0.001). DSB was associated with a diagnosis of CF and COVID-19-related fear (
R
2
= 0.196,
F(13, 124) = 3.169,
p ≤ 0.001). The data suggest that pwCF show functional and adequate behaviors towards the risk caused by the pandemic. Therefore, functional coping behaviors may provide advantages in addressing pandemic challenges.
关键词：encystic fibrosisCOVID-19SARS-CoV-2safety behaviorcopingmental health burden
