摘要:Public health responses to pandemics are concerned with physical impacts as well as emotional reactions, and their relationship with long-term illness and psychological outcomes. Studies from previous pandemics are scarce and indicate that quarantine has both short- and long-term psychological consequences. Emerging studies from COVID-19 paint a similar picture. Most studies have examined individuals either before or following a potential pandemic, thus limiting the understanding of the changes in symptoms over time. The object of the current study was to collect a large global longitudinal online data using weekly assessments, in the early stage of COVID-19 (March - June 2020), with a follow-up assessment at one year. Method: The questionnaires were available in English, Spanish, Italian, and Hebrew using the Qualtrics platform. The first assessments took place in the second half of March 2020 and were followed by 12 weekly assessments. Participants answered questions regarding demographics, COVID-19 symptoms, and diagnosis, quarantine, worry about COVID-19, social media use regarding COVID-19, anxiety (GAD7), depression (PHQ9). PTSD symptoms relating to COVID-19 were assessed at the first and last assessments (PCL5). Results: In total, 1750 participants from over 30 countries answered the initial assessment. Follow-up assessments were completed by approximately 10% of each language group. Risk factors for distress over time will be presented. Conclusions: Implications for mitigating psychological distress during COVID-19 will be discussed.