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  • 标题:Rat Small Intestine Muscle Relaxation Alkaloids from Orixa japonica Leaves
  • 本地全文:下载
  • 作者:Shinji FUNAYAMA ; Rioko TANAKA ; Yasuhiro KUMEKAWA
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:2001
  • 卷号:24
  • 期号:1
  • 页码:100-102
  • DOI:10.1248/bpb.24.100
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:Two quinoline alkaloids, japonine (1) and eduline (2) were isolated from the methanol extract of the leaves of Orixa japonica as relaxants against rat small intestine muscle. The activity of these alkaloids was comparable to that of the typical muscle relaxant papaverine (4). This is also the first report of the isolation of eduline (2) from O. japonica.
  • 关键词:Orixa japonica;quinoline alkaloid;japonine;eduline;rat small intestine;relaxant effect
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