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  • 标题:Testosterone 5α-Reductase Inhibitory Active Constituents from Anemarrhenae Rhizoma
  • 本地全文:下载
  • 作者:Hideaki MATSUDA ; Noriko SATO ; Miho YAMAZAKI
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:2001
  • 卷号:24
  • 期号:5
  • 页码:586-587
  • DOI:10.1248/bpb.24.586
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:The diethyl ether extract of Anemarrhenae Rhizoma (rhizomes of Anemarrhena asphodeloides BUNGE) showed testosterone 5α-reductase inhibitory activity. Two major constituents, cis-hinokiresinol (1) and 2,6,4'-trihydroxy-4-methoxybenzophenone (2) were identified as the active principles. The inhibitory activity of 1 was superior to that of ethinylestradiol, but that of 2 was weak.
  • 关键词:Anemarrhenae Rhizoma;Anemarrhena asphodeloides;testosterone 5α-reductase inhibitor
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