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  • 标题:Ginseng radix Increases Cell Proliferation in Dentate Gyrus of Rats with Streptozotocin-Induced Diabetes
  • 本地全文:下载
  • 作者:Baek-Vin Lim ; Min-Chul Shin ; Mi-Hyeon Jang
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:2002
  • 卷号:25
  • 期号:12
  • 页码:1550-1554
  • DOI:10.1248/bpb.25.1550
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:In the present study, the effect of Ginseng radix on cell proliferation in the dentate gyrus of rats with streptozotocin-induced diabetes was investigated via immunohistochemistry. Aqueous extract of Ginseng radix was shown to exert no significant effect on weight in normal rats, while it prevented weight loss in rats with streptozotocin-induced diabetes. Cell proliferation in the dentate gyrus of diabetic rats was increased by Ginseng radix treatment, but it had no effect on cell proliferation in normal rats. These results suggest that Ginseng radix may help in improve the central nervous system complications of diabetes mellitus.
  • 关键词:Ginseng radix;streptozotocin-induced diabetes;cell proliferation;dentate gyrus
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