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  • 标题:Lethality of Yeasts with Low Pathogenicity in Mice Immunocompromised by Cyclophosphamide Treatment
  • 本地全文:下载
  • 作者:Yoshio Okawa ; Yasuyo Yamada
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:2002
  • 卷号:25
  • 期号:7
  • 页码:940-942
  • DOI:10.1248/bpb.25.940
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:One strain each of Arxiozyma telluris , Saccharomyces cerevisiae , and S. kluyveri showed lethal activity in cyclophosphamide (CY)-treated mice. Accumulation of these yeast cells in the kidneys and elevation of the levels of cytokines, tumor necrosis factor-α, and interleukin-1α in the sera were recognized in the CY-treated infected-debilitated mice.
  • 关键词:yeast;lethality to mice;cyclophosphamide;colony-forming unit;cytokine production
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