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  • 标题:Isolation of Nitrophenols from Diesel Exhaust Particles (DEP) as Vasodilatation Compounds
  • 本地全文:下载
  • 作者:Yoki Mori ; Kazuyuki Kamata ; Noriko Toda
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:2003
  • 卷号:26
  • 期号:3
  • 页码:394-395
  • DOI:10.1248/bpb.26.394
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:The compounds in diesel exhaust particles (DEP) that are responsible for vasodilatation were isolated and characterized for the first time. From benzene extract of DEP, 2-methyl-4-nitrophenol, 3-methyl-4-nitrophenl and 4-nitrophenol were isolated, and their vasodilatation activities were confirmed. 3-methyl-4-nitrophenol caused dilatation of rat thoracic artery, and the other two nitrophenols, also showed vasodilatation activities.
  • 关键词:diesel exhaust particle;nitrophenol;vasodilatation
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