摘要：Bioassay-guided fractionation of the EtOAc-soluble extract of Sedum sarmentosum afforded a new flavonoid, quercetin-3- O -α-(6′′′-caffeoylglucosyl-β-1,2-rhamnoside) (1), along with four known flavonoids, quercetin 3- O -α-(6′′′- p -coumaroylglucosyl-β-1,2-rhamnoside) (2), isorhamnetin-3-β-glucopyranoside (3), quercetin-3-β-glucopyranoside (4), and kaempferol-3-α-arabinopyranoside (5). Purification of these compounds was conducted with the application of various chromatographic methods. Compounds 1—5 inhibited angiotensin I converting enzyme (ACE) activity in a concentration-dependent manner. Compounds 1—5 had 50% inhibitory concentration values of 158.9±11.1 μ M , 351.6±3.9 μ M , 408.9±4.6 μ M , 708.8±23.1 μ M , and 392.8±13.4 μ M .
