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  • 标题:Momordica charantia Extracts Inhibit Uptake of Monosaccharide and Amino Acid across Rat Everted Gut Sacs in-Vitro
  • 本地全文:下载
  • 作者:Mohamad Fawzi Mahomoodally ; Ameenah-Gurib Fakim ; Anwar Hussein Subratty
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:2004
  • 卷号:27
  • 期号:2
  • 页码:216-218
  • DOI:10.1248/bpb.27.216
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:The inhibitory effects of Momordica charantia extracts were studied on the uptake of glucose and tyrosine across rat everted gut sacs in vitro . The aqueous extract of the plant was found to inhibit primarily the uptake of glucose in a dose-dependent manner. Uptake of tyrosine was affected at high substrate concentrations only. The extract was also found to decrease the absorptive capacity of fluid across the small intestine and sodium ions. It is hypothesized that the effects of Momordica could involve a washout of glucose from the blood stream.
  • 关键词:Momordica charantia;glucose;tyrosine;transport;diabetes
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