摘要：In a search for inhibitory components from natural products against NFAT transcription factor, this study investigated the ethyl acetate extract of the fruits of Liquidambar formosana . Four oleanane triterpenoids were isolated and identified to be liquidambaric acid, oleanolic acid, 3α-acetoxy-25-hydroxy-olean-12-en-28-oic acid and lantanolic acid. Of these compounds, 3α-acetoxy-25-hydroxy-olean-12-en-28-oic acid (IC50: 4.63 μ M ) and lantanolic acid (IC50: 12.62 μ M ) exhibited strong inhibitory activity against the NFAT transcription factor.
