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  • 标题:Antiproliferative Constituents from Umbelliferae Plants VII. Active Triterpenes and Rosmarinic Acid from Centella asiatica
  • 本地全文:下载
  • 作者:Miyako Yoshida ; Masahiro Fuchigami ; Tsuneatsu Nagao
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:2005
  • 卷号:28
  • 期号:1
  • 页码:173-175
  • DOI:10.1248/bpb.28.173
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:The antiproliferative constituents in the MeOH extract from the aerial parts of Centella asiatica were investigated. Activity-guided fractionation of MeOH extract resulted in the isolation of ursolic acid lactone, ursolic acid, pomolic acid, 2α,3α-dihydroxyurs-12-en-28-oic acid, 3-epimaslinic acid, asiatic acid, corosolic acid, and rosmarinic acid. Antiproliferative activity of the isolated compounds against human gastric adenocarcinoma (MK-1), human uterine carcinoma (HeLa), and murine melanoma (B16F10) cells was estimated.
  • 关键词:Centella asiatica;antiproliferative activity;Umbelliferae;triterpene
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