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  • 标题:Essential Oil Composition, Antibacterial and Antioxidant Activity of the Oil and Various Extracts of Ziziphora clinopodioides subsp. rigida (BOISS.) RECH. f. from Iran
  • 本地全文:下载
  • 作者:Peyman Salehi ; Ali Sonboli ; Fereshteh Eftekhar
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:2005
  • 卷号:28
  • 期号:10
  • 页码:1892-1896
  • DOI:10.1248/bpb.28.1892
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:The chemical composition of the essential oil obtained from the aerial parts of Z. clinopodioides subsp. rigida (B OISS .) R ECH . f. was analysed by GC and GC-MS. Thirty-one constituents accounting to 99.5% of the total oil were identified. Oxygenated monoterpenes (93.3%) were the predominant portion of the oil with pulegone (45.8%), piperitenone (17.4%), p -menth-3-en-8-ol (12.5%) and thymol (8.0%) as the main constituents. Antibacterial activity of the oil and its two main compounds and various extracts of plant were tested against seven Gram-(+) or Gram-(−) bacteria. It was found that the oil and MeOH extract (M) exhibited interesting antibacterial activity. The samples were also subjected to screening for their possible antioxidant activity by using 2,2-diphenyl-1-picrazylhydrazyl (DPPH) assay. The free radical scavenging activity of MeOH extract (M) was superior to all other extracts (IC50=30.7 μg/ml), while the oil was less effective.
  • 关键词:essential oil composition;pulegone;antibacterial activity;antioxidant activity;Ziziphora clinopodioides subsp. rigida;Labiatae
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