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  • 标题:Antiallergic, Antipyretic, Hypoglycemic and Hepatoprotective Effects of Aqueous Extract of Coronopus didymus LINN
  • 本地全文:下载
  • 作者:Sudheer Kumar Mantena ; Srinivasa Mutalik ; Hullegala Srinivasa
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:2005
  • 卷号:28
  • 期号:3
  • 页码:468-472
  • DOI:10.1248/bpb.28.468
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:The aqueous extract of whole plant of Coronopus didymus L INN (CD) [Family: Bracicacea] was screened for antiallergic, antipyretic and hepatoprotective effects in rats and hypoglycemic activity in mice. The extract showed significant antiallergic, antipyretic, hypoglycemic and hepatoprotective activity at 200 and 400 mg/kg doses on oral administration. Mechanistically, CD acts as an antioxidant as evidenced by its ability to scavenge DPPH and superoxide radicals. All the observed activities may be due to the presence of flavonoids, saponins and tannins as they are reported to possess a variety of biological activities.
  • 关键词:Coronopus didymus;antiallergic;antipyretic;hypoglycemic;hepatoprotective
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