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  • 标题:Hepatoprotective Activity of the Constituents in Swertia pseudochinensis
  • 本地全文:下载
  • 作者:Jian-Chen Li ; Li Feng ; Bao-Hui Sun
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:2005
  • 卷号:28
  • 期号:3
  • 页码:534-537
  • DOI:10.1248/bpb.28.534
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:A new xanthone derivative was isolated together with other 13 known constituents from a Chinese natural medicine, Swertia pseudochinensis H ARA . Their structures were determined based on the spectral and chemical evidences. Furthermore, respective hexane, ethyl acetate, 1-BuOH, MeOH and water extracts of S. pseudochinensis , and purified compounds were respectively evaluated for their hepatoprotective activities against hepatocyte injury induced by CCl4. All the extracts and isolated compounds exhibited significant hepatoprotective activities at a dose showing no hepatoxicity.
  • 关键词:Swertia pseudochinensis;hepatoprotective activity;hepatoxicity
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