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  • 标题:Production of Catechol-Siderophore and Utilization of Transferrin-Bound Iron in Bacillus cereus
  • 本地全文:下载
  • 作者:Ra-Young Park ; Mee-Hwa Choi ; Hui-Yu Sun
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:2005
  • 卷号:28
  • 期号:6
  • 页码:1132-1135
  • DOI:10.1248/bpb.28.1132
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:In the present study we attempted to ascertain whether Bacillus cereus was able to produce catechol-siderophore(s), and whether it was able to utilize transferrin-bound iron. The growth of B. cereus was stimulated in proportion to the iron-saturation level of the transferrin, and catechol-siderophores were produced in inverse proportion to this level. B. cereus was proved to uptake iron from partially iron-saturated transferrin or holotransferrin, without destroying the transferrin by its proteases. The catechol-siderophores from B. cereus were able to sustain and augment its growth on the transferrin-bound iron. These results indicate that B. cereus has the ability to produce catechol-siderophores, and to utilize transferrin-bound iron as an iron source for growth, via the siderophore-mediated iron-uptake system.
  • 关键词:Bacillus cereus;transferrin;iron;siderophore
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