摘要：The yield of methanolic extract and total phenol and non polar content of flowered parts from Achillea ligustica A LL . are reported. GC-MS analysis of the non polar fraction showed that the triterpene moretenol was the major constituent (17.228%) followed by stigmast-6-en-3β-ol, veridiflorol and β-amyrin (7.524%, 5.078% 4.470%, respectively). The antioxidant activities of the methanolic extract and its fractions from A. ligustica were carried out using two different in vitro assays, 2,2-diphenyl-1-picrylhydrazyl (DPPH) test and lipid peroxidation of liposomes assay. Methanolic extract showed higher radical scavenging activity on DPPH (IC50 of 50 μg/ml). This activity is probably due to the phenolic fraction which shown an IC50 value of 22 μg/ml. A different result was obtained from the methanolic extract on the lipid peroxidation of liposomes (IC50 of 416 μg/ml). The α-amylase inhibition assay was applied to evaluate antidiabetic activity. The methanolic extract showed weak activity (28.18% at 1 mg/ml) while the n -hexane fraction showed 74.96% inhibition at 250 μg/ml.
