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  • 标题:The Anti-Helicobacter pylori Flavones in a Brazilian Plant, Hyptis fasciculata, and the Activity of Methoxyflavones
  • 本地全文:下载
  • 作者:Takahiko Isobe ; Matsumi Doe ; Yoshiki Morimoto
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:2006
  • 卷号:29
  • 期号:5
  • 页码:1039-1041
  • DOI:10.1248/bpb.29.1039
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:Two known flavonoids were isolated from a tropical medicinal plant, Hyptis fasciculata (Labiatae), found in Brazil. Flavonoids were identified as cirsilineol (1) and cirsimaritin (2) by spectroscopic means and were exhibited potent antibacterial activity against Helicobacter pylori , and cirsilineol (1) had weak antibacterial activity against Escherichia coli and Salmonella enteritidis . Following up on the relationship between anti- H. pylori activity and flavonoids with methoxy groups, several methoxy flavonoids were evaluated for proliferation of H. pylori .
  • 关键词:Helicobacter pylori;flavone;Hyptis fasciculata;methoxy;Labiatae
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