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  • 标题:Solubilization of Dipropofol, an Antibacterial Agent, Using Saccharide and Ascorbic Acid
  • 本地全文:下载
  • 作者:Masahiro Ogata ; Kentaro Oka ; Masako Seki
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:2007
  • 卷号:30
  • 期号:8
  • 页码:1565-1568
  • DOI:10.1248/bpb.30.1565
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:Dipropofol has a strong antibacterial activity against Gram-positive bacteria. However, it lacked the solubility in water and this property was supposed to limit its efficacy. We tried to improve the solubility and found a new solubilization method of dipropofol in water by the addition of a monosaccharide or ascorbic acid.
  • 关键词:dipropofol;monosaccharide;ascorbic acid;solubilization
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