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  • 标题:Inhibitory Effects of Three-Component Hybrid Liposomes Containing Cationic Lipids without Drugs on the Growth of Human Renal Tumor Cells in Vitro
  • 本地全文:下载
  • 作者:Masayo Umebayashi ; Yoko Matsumoto ; Ryuichi Ueoka
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:2008
  • 卷号:31
  • 期号:9
  • 页码:1816-1817
  • DOI:10.1248/bpb.31.1816
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:The inhibitory effects of three-component hybrid liposomes (HL) containing cationic lipids on the growth of human renal tumor cells were examined. Fifty percent inhibitory concentration of the three-component HL was remarkably reduced compared with that of dimyristoylphosphatidylcholine liposomes. The induction of apoptosis by the three-component HL without antitumor drugs was obtained for human renal tumor cells for the first time in this study.
  • 关键词:liposome;apoptosis;renal tumor
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