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  • 标题:Total Peroxynitrite Scavenging Capacity of Phenylethanoid and Flavonoid Glycosides from the Flowers of Buddleja officinalis
  • 本地全文:下载
  • 作者:Bui Huu Tai ; Bong Yong Jung ; Nguyen Manh Cuong
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:2009
  • 卷号:32
  • 期号:12
  • 页码:1952-1956
  • DOI:10.1248/bpb.32.1952
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:Nine compounds, including six phenylethanoid glycosides: acteoside (1); bioside (2); echinacoside (3); poliumoside (4); phenylethyl glycoside (5); salidroside (6) and three flavonoids; linarin (7); apigenin (8); isorhoifolin (9), were isolated from the flowers of Buddleja officinalis M AXIM . (Buddlejaceae). Chemical structures were confirmed by 1H-, and 13C-NMR, and MS spectral methods and compared with those reported in the literature. Antioxidant activities of the methanol and water extracts, and all isolated compounds were evaluated using the total oxidant scavenging capacity (TOSC) assay against peroxynitrite. Results of the assay showed that the phenylethanoid glycosides, a major class of compounds of the flowers of B. officinalis , possess strong antioxidant activity. Of these, acteoside, echinacoside and poliumoside have 9.9-, 9.8- and 9.5-fold TOSC value, respectively, compared with the positive control, Trolox.
  • 关键词:phenylethanoid;flavonoid;peroxynitrite;antioxidant;Buddleja officinalis
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