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  • 标题:Composio química e avaliao das atividades antioxidante e anticolinesterásica do óleo dos frutos de Ouratea fieldingiana (Gargner) Engl.
  • 本地全文:下载
  • 作者:Lucas Soares Frota ; Francisco Flavio Sousa Lopes ; Daniela Ribeiro Alves
  • 期刊名称:Research, Society and Development
  • 电子版ISSN:2525-3409
  • 出版年度:2021
  • 卷号:10
  • 期号:10
  • 页码:1-11
  • DOI:10.33448/rsd-v10i10.19013
  • 语种:English
  • 出版社:Grupo de Pesquisa Metodologias em Ensino e Aprendizagem em Ciências
  • 摘要:The medicinal plant Ouratea fieldinfiana popularly known as batiputá, is commonly found in the coastal region of Ceará, belonging to the Ochnaceae family and with arboreal or shrubby characteristics, an oil can be extracted from its fruit that is used in cooking and in traditional medicine as an anti-inflammatory. This work aimed to characterize the batiputá oil and the polar fraction of this oil, as well as to quantify the total phenols, evaluate its antioxidant and anticholinesterase capacity. From the artisanal batiputá oil obtained by a rural resident in the city of Trairi-CE, its polar fraction was separated by decantation with methanol and hexane. The main fatty acids of the oil were identified by GC-MS in the batiputá oil were palmitic (24.55%), linoleic (20.02%) and oleic (30.81%) acids. The polar fraction of the oil was characterized in HPLC-DAD, being constituted by the flavone apigenin and its amentoflavone dimer. The polar fraction presented a good amount of total phenols, with 138.78 mg/EAG per gram of the fraction, in addition to an excellent antioxidant capacity with IC50 of 5.66 and 4.42 to inhibit DPPH* and ABTS*+ radicals, respectively. The fraction still has an almost three times greater capacity to inhibit acetylcholinesterase, needing 12.58 μg/mL of the fraction, while the oil needs 36.66 μg/mL for its inhibitory effect. These results show that the polar fraction of batiputá oil has a strong potential to be a commercial antioxidant and its anticholinesterase effect may guide further studies to better understand its effect against neurodegenerative diseases.
  • 关键词:Ochnaceae;Fixed oil;Phenols;Antioxidant;Acetylcholinesterase.
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